If the Save function is not visible within the program's toolbar, you may need to reset your toolbar to ensure that all the latest options (and any functions which were previously hidden) are displayed.
You can reset the toolbar of a specific program in SYSPRO by selecting the program's Customize option from the Add or Remove buttons submenu (available from the small drop down arrow located at the far right end of the toolbar).
Alternatively, you can reset the toolbars of all programs, by selecting the Reset Toolbar Settings function from the Toolbars tab of the Personalize program (SYSPRO Ribbon bar > Home > Personalization).